Combined Lamivudine and Hepatitis B Immunoglobulin for the Prevention of Hepatitis B Recurrence after Liver Transplantation: Long-Term Results

prevention of hepatitis b recurrence in liver transplant patients using oral antiviral therapy without long-term hepatitis b immunoglobulin

Prevention of Hepatitis B Recurrence in Liver Transplant Patients Using Oral Antiviral Therapy without Long-Term Hepatitis B Immunoglobulin

BACKGROUND Small studies have suggested that nucleos(t)ide analogue therapy (NAT) with reduced hepatitis B immunoglobulin (HBIG) duration may be efficacious in preventing post-liver transplantation (LT) HBV recurrence. OBJECTIVES This larger study evaluates the use of NAT with short term (< 6 mo) or no HBIG for prevention of post-LT HBV recurrence. PATIENTS AND METHODS All HBV patients unde...

Is Hepatitis B Immunoglobulin Necessary in Prophylaxis of Hepatitis B Recurrence after Liver Transplantation? A Meta-Analysis

BACKGROUND & AIMS Application of nucleoside analogues and hepatitis B immunoglobulin (HBIG) has reduced hepatitis B virus (HBV) recurrence rate after liver transplantation (LT) dramatically. Recent data suggests therapy without HBIG is also effective. We sought to evaluate the necessity of HBIG in prophylaxis of HBV recurrence after LT. METHODS A meta-analysis was performed. PubMed/MEDLINE, W...

Prevention and Treatment of Recurrent Hepatitis B after Liver Transplantation

Chronic hepatitis B is a global health problem that leads to development of various complications, such as cirrhosis, liver cancer, and liver failure requiring liver transplantation. The recurrence of hepatitis B virus (HBV) post-liver transplantation is a major cause of allograft dysfunction, cirrhosis of the allograft, and graft failure. Patients with high viral load at the time of transplant...

Hepatitis B Prevention and Immunization

هپاتیت به معنی التهاب کبد است. هپاتیت B هپاتیت سرمی هم نامیده می شود، ویروس آن از خون، مایعات سروزی بدن، بزاق و مایع منی یافت شده و باعث می گردد که سلولهای کبدی به دنبال واکنش التهابی عملکرد خود را از دست دهند که این حالت ممکن است منجر به انسداد مجاری صفراوی و یا نارسایی کبد شود.